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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
abbomax//100 ug/604-040
产品编号:604-040
市  场 价:¥4900.00
场      地:美国(厂家直采)
产品分类: 蛋白类>多肽>多肽合成>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$245.00
品      牌: abbomax
公      司:abbomax
公司分类:
abbomax//100 ug/604-040
商品介绍
AID
Product Preparation
Background
AID, also known as Activation-induced cytidine deaminase, an RNA-editing deaminase, is a 24 kDa enzyme that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion (in chickens, pigs, etc.), and class-switch recombination of immunoglobulin genes. It creates mutations in DNA by deamination of cytosine base, which turns it into uracil which is recognized as a thymine. AID plays a critical role during B cell development. Protein is normally expressed in germinal center B cells, its forced expression in B cells at the wrong stage of differentiation, in non-B cells, and in Escherichia coli results in enhanced mutagenesis and mutational spectra mimicking somatic hypermutation (SHM). Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2). Overexpression correlates with poor prognosis in chronic lymphocytic leukemia and lymphoma
PURIFICATION
The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping
SPECIFICITY
FORMULATION
STORAGE
Gene ID
Applications/Suggested Working Dilutions
Western Blot
0.1-1 µg/ml
ELISA
0.01-0.1 µg/ml
Immunoprecipitation
2-5µg/ml
IHC
2-10µg/ml
Flow cytometry
5-10µg/ml
品牌介绍

AbboMax美国ABBOMAX公司是全面的抗体供应厂家,目前可提供的抗体种类多达50000多种,几乎覆盖了目前生命科学研究的各个新领域,还提供相关产品,如:所以一抗产品的标记,各种标记二抗等,为免疫学研究工作提供了极大的方便。

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