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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
abbomax//100 ug/604-010
产品编号:604-010
市  场 价:¥4900.00
场      地:美国(厂家直采)
产品分类: 蛋白类>多肽>多肽合成>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$245.00
品      牌: abbomax
公      司:abbomax
公司分类:
abbomax//100 ug/604-010
商品介绍
4E-BP1
Product Preparation
Background
4E-BP1 eukaryotic initiation factor 4E binding protein 1 is a member of a family of translation repressor proteins. It inhibits cap-dependent translation by binding to the translation initiation factor eIF4E. In the unphosphorylated form, it suppresses the translation initiation of capped mRNAs, whereas in phosphorylated form, it increases translation initiation. Several kinases phosphorylate 4E-BP1 dependent or independent of mTOR, indicating that mTOR may not be the only kinase that phosphorylates 4E-BP1. It is a multi-functional protein, in addition to translation repression, under certain cellular conditions it may also play a role as a tumor promoter. The protein is involved in tumorigenesis and is overexpressed in various carcinomas.
PURIFICATION
The mouse IgG is purified by Protein A-Affinity Chromatography according to Isotyping
SPECIFICITY
FORMULATION
STORAGE
Gene ID
Applications/Suggested Working Dilutions
Western Blot
0.1-1 µg/ml
ELISA
0.01-0.1 µg/ml
Immunoprecipitation
2-5µg/ml
IHC
2-10µg/ml
Flow cytometry
5-10µg/ml
品牌介绍

AbboMax美国ABBOMAX公司是全面的抗体供应厂家,目前可提供的抗体种类多达50000多种,几乎覆盖了目前生命科学研究的各个新领域,还提供相关产品,如:所以一抗产品的标记,各种标记二抗等,为免疫学研究工作提供了极大的方便。

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