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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
abbomax//100 ug/602-160
产品编号:602-160
市  场 价:¥4900.00
场      地:美国(厂家直采)
产品分类: 蛋白类>多肽>多肽合成>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$245.00
品      牌: abbomax
公      司:abbomax
公司分类:
abbomax//100 ug/602-160
商品介绍
CDC2 (pY15) (CDK1)
Cyclin-Dependent Kinase 1; CDK1
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Product Preparation
A synthetic peptide surrounding to the epitope-GTYGV- with a phosphorylation site atTyr15 of human CDC2 protein. This sequence is identical amonghuman, mouse, rat, bovine and chicken species.
Background
Cyclins and cyclin-dependent kinases (CDKs) control cell cycle progression by phosphorlating regulatory proteins. These cyclin-related proteins appear to affect cell structure and function independent of the cell cycle. Cyclins and CDKs have a role in the development and maintenance of cell- and tissue-restricted properties of differentiated cells. CDC2 (Cell Division Cycle 2), also known as CDK1 (Cyclin Dependent kinase 1), is a member of the CDK family of serine/threonin kinases. It is a highly conserved serine protein kinase that plays a key role in regulation of the cell cycle.  The phosphorylation of CDC2 at Y15 and T14 during the G2 phase of the cell cycle inhibits CDC2 activity, while the dephosphorylation of Y15 and T14 by CDC25 phosphatase during the late G2 restores its activity.
PURIFICATION
The Rabbit IgG is purified by site-modified Epitope Affinity Purification.
SPECIFICITY
This antibodyrecognizesCDC2 (pY15) with aphosphorylated site at Tyrosine 15. It does not cross-react with non-phosphospecific peptide.
FORMULATION
This affinity purified antibody is supplied in sterile Tris-buffered saline (pH7.2) containing antibody stabilizer.
STORAGE
The antibodies are stable for 12 months from date of receipt when stored at –20oC. The antibodies can be stored at 2oC-8oC for one month without detectable loss of activity.Avoid repeated freezing-thawing cycles.
Gene ID
983
Applications/Suggested Working Dilutions
Western Blot
0.1-1 µg/ml
ELISA
0.01-0.1 µg/ml
Immunoprecipitation
2-5µg/ml
IHC
2-10µg/ml
Flow cytometry
5-10µg/ml
品牌介绍

AbboMax美国ABBOMAX公司是全面的抗体供应厂家,目前可提供的抗体种类多达50000多种,几乎覆盖了目前生命科学研究的各个新领域,还提供相关产品,如:所以一抗产品的标记,各种标记二抗等,为免疫学研究工作提供了极大的方便。

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