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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
abbomax/EWSR/100ug/600-820
产品编号:600-820
市  场 价:¥0.00
场      地:美国(厂家直采)
产品分类: 抗体类>一抗>内参抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$225.00
品      牌: abbomax
公      司:abbomax
公司分类:
abbomax/EWSR/100ug/600-820
商品介绍
EWSR
EWSR1; Ewing sarcoma breakpoint region 1
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Product Preparation
A synthetic peptide corresponding to the internal segment of EWSR1 protein.This sequence is identical among human, rat, mouse and dog species.
Background
The EWSR1 gene encodes a putative RNA binding protein. Mutation in this gene causes Ewing sarcoma and neuroectodermal and various other tumors. This gene is involved in a number of different sarcomas as a result of chromosomal translocations. EWSR1 is fused to an ETS transcription factor (FLI-1, ERG, ETV-1, E1AF or FEV) in Ewing sarcoma; to activating transcription factor-1 (ATF-1) in soft tissue clear cell sarcoma; to Wilms Tumor -1 (WT1) in desmoplastic small round cell; to nuclear receptor 4A3 (NR4A3) in extraskeletal myxoid chondrosarcoma, and to C/EBP-homologous protein (CHOP) in myxoid liposarcoma. EWSR1 genes are required for mitotic integrity and survival of neural cells in the early embryonic development, and that the involvement of EWSR1 in mitotic stability is conserved from zebrafish to human.
PURIFICATION
The Rabbit IgG is purified by Epitope Affinity Purification
SPECIFICITY
This antibody recognizes ~70 kDa of EWSR1 protein. It also cross reacts with human, mouse and rat tissues. The other species are not tested.
FORMULATION
This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
STORAGE
The antibodies are stable for 12 months from date of receipt when stored at –20oC. The antibodies can be stored at 2oC-8oC for one month without detectable loss of activity.Avoid repeated freezing-thawing cycles.
Gene ID
Q01844.1
Applications/Suggested Working Dilutions
Western Blot
0.1-1 µg/ml
ELISA
0.01-0.1 µg/ml
Immunoprecipitation
2-5µg/ml
IHC
2-10µg/ml
Flow cytometry
5-10µg/ml
品牌介绍

AbboMax美国ABBOMAX公司是全面的抗体供应厂家,目前可提供的抗体种类多达50000多种,几乎覆盖了目前生命科学研究的各个新领域,还提供相关产品,如:所以一抗产品的标记,各种标记二抗等,为免疫学研究工作提供了极大的方便。

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