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产品名称：abbomax/JAK2(pY1007/Y1008)/100ug/620-150

产品编号：620-150

市场价：¥0.00

场地：美国(厂家直采)

产品分类：抗体类>一抗>内参抗体>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$270.00

品牌： abbomax

公司：abbomax

公司分类：

商品介绍

JAK2(pY1007/Y1008)

Janus kinase 2

Download Product PDF

Product Preparation

A synthetic peptide surrounding to the epitope-EYYK- withdual phosphorylation sites at Tyr1007 and Tyr1008 of JAK2 from human, mouse and rat origins

Background

The Janus tyrosine kinase family is consists of four members, JAK1, JAK2, JAK3 and Tyk2. Upon the cytokine ligand binding to its the receptors, the dimerization of the receptors occurs followed by phosphorylation of the receptors. The phosphorylation of receptors recruites the tyrosine kinase physically associated to the dimerized receptors, and phosphorylate the kinase, thus activates the signal transducer and activator of thranscription (STAT1, 3, 5) and the other signal proteins.

PURIFICATION The Rabbit IgG is purified by site-modified Epitope Affinity Purification.	SPECIFICITY This antibody recognizes JAK2 with dual phosphorylated sites of Tyr1007/1008. It does not cross-react with non-phosphospecific peptide.
FORMULATION This affinity purified antibody is supplied in sterile Tris-buffered saline (pH7.2) containing antibody stabilizer.	STORAGE The antibodies are stable for 12 months from date of receipt when stored at –20oC. The antibodies can be stored at 2oC-8oC for one month without detectable loss of activity.Avoid repeated freezing-thawing cycles.

Gene ID

3717

Applications/Suggested Working Dilutions

Western Blot

0.1-1 µg/ml

ELISA

0.01-0.1 µg/ml

Immunoprecipitation

2-5µg/ml

IHC

2-10µg/ml

Flow cytometry

5-10µg/ml

品牌介绍

AbboMax美国ABBOMAX公司是全面的抗体供应厂家，目前可提供的抗体种类多达50000多种，几乎覆盖了目前生命科学研究的各个新领域，还提供相关产品，如：所以一抗产品的标记，各种标记二抗等，为免疫学研究工作提供了极大的方便。

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