abbomax/FAK(pY576)/100ug/600-320,abbomax,,abbomax,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：abbomax/FAK(pY576)/100ug/600-320

产品编号：600-320

市场价：¥0.00

场地：美国(厂家直采)

产品分类：抗体类>一抗>抗体套装>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$230.00

品牌： abbomax

公司：abbomax

公司分类：

商品介绍

FAK(pY576)

Focal adhesion kinase

Download Product PDF

Product Preparation

A synthetic peptide surrounding to the epitope-STYYKA- with a phosphorylation site atTyrosine 576 of human FAK protein. This sequence is identical among human, mouse and rat.

Background

Focal adhesion kinase (FAK) gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinase but lacks significant sequence similarity to kinase from other subfamilies. Activation by phosphorylation of Y397, Y576/577 and Y863 of FAK protein may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Increased FAK expression has been correlated with the enhanced motility and invasiveness of human tumor cells, as well as with promoting increased cell proliferation

PURIFICATION The Rabbit IgG is purified by site-modified Epitope Affinity Purification.	SPECIFICITY This antibodyrecognizes FAK (pY576) with aphosphorylated site at Tyrosine576. It does not cross-react with non-phosphospecific peptide.
FORMULATION This affinity purified antibody is supplied in sterile Tris-buffered saline (pH7.2) containing antibody stabilizer.	STORAGE The antibodies are stable for 12 months from date of receipt when stored at –20oC. The antibodies can be stored at 2oC-8oC for one month without detectable loss of activity.Avoid repeated freezing-thawing cycles.

Gene ID

25614

Applications/Suggested Working Dilutions

Western Blot

0.1-1 µg/ml

ELISA

0.01-0.1 µg/ml

Immunoprecipitation

2-5µg/ml

IHC

2-10µg/ml

Flow cytometry

5-10µg/ml

品牌介绍

AbboMax美国ABBOMAX公司是全面的抗体供应厂家，目前可提供的抗体种类多达50000多种，几乎覆盖了目前生命科学研究的各个新领域，还提供相关产品，如：所以一抗产品的标记，各种标记二抗等，为免疫学研究工作提供了极大的方便。

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